USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P07195 USC-OGP 2-DE database:  P07195 P07195 General information about the entry View entry in simple text format Entry name LDHB_HUMAN Primary accession number P07195 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=L-lactate dehydrogenase B chain; Short=LDH-B; EC=1.1.1.27; AltName: Full=LDH heart subunit; Short=LDH-H; AltName: Full=Renal carcinoma antigen NY-REN-46;. Gene name Name=LDHB Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0412: pI=5.53; Mw=42022 SPOT OGP-0448: pI=5.54; Mw=35854 SPOT OGP-0455: pI=5.42; Mw=34819 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0711: pI=5.55; Mw=42162 SPOT OGP-0730: pI=5.43; Mw=36140 SPOT OGP-0736: pI=5.56; Mw=35605 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1210: pI=5.74; Mw=37929 SPOT OGP-1215: pI=5.57; Mw=36464 SPOT OGP-1218: pI=5.73; Mw=36260 SPOT OGP-1222: pI=5.73; Mw=35353 SPOT OGP-1228: pI=6.90; Mw=34761 Cross-references UniProtKB/Swiss-Prot P07195; LDHB_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name LDHB_HUMAN Primary accession number P07195 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 203) Name and origin of the protein Description RecName: Full=L-lactate dehydrogenase B chain; Short=LDH-B; EC=1.1.1.27; AltName: Full=LDH heart subunit; Short=LDH-H; AltName: Full=Renal carcinoma antigen NY-REN-46; Gene name Name=LDHB Encoded on Name=LDHB Keywords 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; NAD; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X13794; CAA32033.1; -; Genomic_DNA EMBL X13795; CAA32033.1; JOINED; Genomic_DNA EMBL X13796; CAA32033.1; JOINED; Genomic_DNA EMBL X13797; CAA32033.1; JOINED; Genomic_DNA EMBL X13798; CAA32033.1; JOINED; Genomic_DNA EMBL X13799; CAA32033.1; JOINED; Genomic_DNA EMBL X13800; CAA32033.1; JOINED; Genomic_DNA EMBL Y00711; CAA68701.1; -; mRNA EMBL BC002362; AAH02362.1; -; mRNA EMBL BC015122; AAH15122.1; -; mRNA EMBL BC071860; AAH71860.1; -; mRNA CCDS CCDS8691.1; -; . PIR S02795; DEHULH; . RefSeq NP_001167568.1; NM_001174097.2; . RefSeq NP_001302466.1; NM_001315537.1; . RefSeq NP_002291.1; NM_002300.7; . UniGene Hs.446149; -; . PDB 1I0Z; X-ray; 2.10 A; A/B=2-334 PDB 1T2F; X-ray; 3.00 A; A/B/C/D=2-332 PDBsum 1I0Z; -; . PDBsum 1T2F; -; . ProteinModelPortal P07195; -; . SMR P07195; -; . BioGrid 110137; 135; . IntAct P07195; 29; . MINT MINT-1144561; -; . STRING 9606.ENSP00000229319; -; . BindingDB P07195; -; . ChEMBL CHEMBL4940; -; . DrugBank DB00157; NADH; . DrugBank DB03940; Oxamic Acid; . iPTMnet P07195; -; . PhosphoSitePlus P07195; -; . SwissPalm P07195; -; . BioMuta LDHB; -; . DMDM 126041; -; . DOSAC-COBS-2DPAGE P07195; -; . OGP P07195; -; . REPRODUCTION-2DPAGE IPI00219217; -; . SWISS-2DPAGE P07195; -; . UCD-2DPAGE P07195; -; . EPD P07195; -; . PaxDb P07195; -; . PeptideAtlas P07195; -; . PRIDE P07195; -; . TopDownProteomics P07195; -; . DNASU 3945; -; . Ensembl ENST00000350669; ENSP00000229319; ENSG00000111716; . Ensembl ENST00000396076; ENSP00000379386; ENSG00000111716; . GeneID 3945; -; . KEGG hsa:3945; -; . CTD 3945; -; . DisGeNET 3945; -; . GeneCards LDHB; -; . HGNC HGNC:6541; LDHB; . HPA CAB004641; -; . HPA HPA019007; -; . MalaCards LDHB; -; . MIM 150100; gene; . MIM 614128; phenotype; . neXtProt NX_P07195; -; . OpenTargets ENSG00000111716; -; . Orphanet 284435; Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency; . PharmGKB PA30325; -; . eggNOG KOG1495; Eukaryota; . eggNOG COG0039; LUCA; . GeneTree ENSGT00550000074541; -; . HOGENOM HOG000213793; -; . HOVERGEN HBG000462; -; . InParanoid P07195; -; . KO K00016; -; . OMA CNDKLQG; -; . OrthoDB EOG091G0HME; -; . PhylomeDB P07195; -; . TreeFam TF314963; -; . BRENDA 1.1.1.27; 2681; . Reactome R-HSA-70268; Pyruvate metabolism; . SABIO-RK P07195; -; . UniPathway UPA00554; UER00611; . ChiTaRS LDHB; human; . EvolutionaryTrace P07195; -; . GenomeRNAi 3945; -; . PRO PR:P07195; -; . Proteomes UP000005640; Chromosome 12; . Bgee ENSG00000111716; -; . CleanEx HS_LDHB; -; . ExpressionAtlas P07195; baseline and differential; . Genevisible P07195; HS; . GO GO:0005737; C:cytoplasm; TAS:UniProtKB; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0045121; C:membrane raft; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IEA:Ensembl; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0004459; F:L-lactate dehydrogenase activity; EXP:Reactome; . GO GO:0051287; F:NAD binding; IEA:Ensembl; . GO GO:0005975; P:carbohydrate metabolic process; IEA:InterPro; . GO GO:0006089; P:lactate metabolic process; IEA:Ensembl; . GO GO:0019674; P:NAD metabolic process; IEA:Ensembl; . GO GO:0006090; P:pyruvate metabolic process; TAS:Reactome; . Gene3D 3.40.50.720; -; 1; . Gene3D 3.90.110.10; -; 1; . HAMAP MF_00488; Lactate_dehydrog; 1; . InterPro IPR001557; L-lactate/malate_DH; . InterPro IPR011304; L-lactate_DH; . InterPro IPR018177; L-lactate_DH_AS; . InterPro IPR022383; Lactate/malate_DH_C; . InterPro IPR001236; Lactate/malate_DH_N; . InterPro IPR015955; Lactate_DH/Glyco_Ohase_4_C; . InterPro IPR016040; NAD(P)-bd_dom; . Pfam PF02866; Ldh_1_C; 1; . Pfam PF00056; Ldh_1_N; 1; . PIRSF PIRSF000102; Lac_mal_DH; 1; . PRINTS PR00086; LLDHDRGNASE; . SUPFAM SSF51735; SSF51735; 1; . SUPFAM SSF56327; SSF56327; 1; . TIGRFAMs TIGR01771; L-LDH-NAD; 1; . PROSITE PS00064; L_LDH; 1; .

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